Mar 31, 2021 · We added 250 mg of patiromer to 50 mL of NS in a conical vial and suspended by vortex mixing. We added aliquots of 0.4, 0.8, 2.0, 4.0, and 20 mL of this stock suspension to conical vials and volume balanced with NS to a total of 20 mL, achieving concentrations of 0.1, 0.2, 0.5, 1.0, and 5.0 mg/mL of patiromer in NS.